12 Best Restaurants in Biloxi, Mississippi

Last Updated on February 19, 2024 by Emily Johnson

Biloxi is a charming coastal city located along the Mississippi Gulf Coast that is known for its sandy beaches, historic sites, museums, and of course, amazing seafood. As a popular tourism destination, Biloxi offers no shortage of incredible dining opportunities to satisfy every palate.

From longstanding institutions serving up quintessential Southern fare to contemporary eateries putting unique twists on regional classics, Biloxi’s vibrant and diverse food scene has something for everyone.

As the seafood capital of Mississippi, it’s no surprise that Biloxi offers some of the freshest catches from the Gulf as well as time-honored shrimp, oyster, and crawfish boils.

However, the city’s culinary landscape encompasses so much more – from old school meat-and-threes dishing up stick-to-your-ribs comfort food to ethnic eateries transporting diners around the globe one bite at a time. Barbecue joints, bistros, steakhouses, pintxos bars, po’ boy shops, bakeries, and more round out this exceptional array of eateries.

The following are 12 of the best, must-try restaurants in Biloxi showcasing the city’s eclectic tastes and flavors. From special occasion fine dining to casual cafes, waterfront views to neighborhood gems, this list offers a round-up of the most mouthwatering destinations for unforgettable meals in Biloxi.

1. The Half Shell Oyster House

For over a decade, The Half Shell Oyster House has been a go-to for impeccably fresh Gulf seafood in Biloxi. Situated right on Beach Boulevard with panoramic views over the Mississippi Sound, this ever-popular restaurant lives up to its stellar reputation with an extensive raw bar starring oysters from both coasts alongside chilled shrimp, clams, mussels and Louisiana blue crab claws.

Mains run the gamut from fried platters and po’ boys to blackened, bronzed and grilled catches like snapper, catfish and mahi mahi tacos. Daily chalkboard specials such as the fiery boiled buckets brimming with head-on shrimp, Dungeness crab, crawfish, sausage, corn and potatoes are always a solid bet.

With free oysters during happy hour, weekend brunch featuring Cajun takes on breakfast classics, and live music acts keeping the mood festive, Half Shell consistently delivers good times and great flavors.

Address: 285 Beach Blvd, Biloxi, MS 39530

Hours: Sun-Thu, 11am–10pm; Fri-Sat, 11am–11pm

Contact: (228) 271-9950; halfshelloysterhouse.com

2. The Blind Tiger

Nuzzled on the first floor of the new Biloxi Boardwalk Marina Hotel, this contemporary gastropub instantly made waves on the local dining scene when it opened its doors in 2020. The colorful, art deco-inspired space sets the stage for globally inspired small plates and handcrafted drinks paying homage to prohibition-era speakeasies.

With a seasonally changing lineup, the menu sees Latin flavors in items like empanadas and chipotle chicken tacos, Vietnamese influences in the banh mi sandwich, and Southern soul in BBQ baby back ribs and fried green tomatoes with pimento cheese.

Among dozens of craft cocktails and local beers, the “Saintsational” frozen Irish coffee and Biloxi Banana Hammer are especially showstopping. Thanks to its prime location and vibrant energy, The Blind Tiger is a stellar spot for savoring Biloxi’s emerging culinary creativity.

Address: 13635 Jamey Ryan Blvd C, Biloxi, MS 39532

Hours: Daily, 11am–10pm

Contact: (228) 207-3113; biloxiboardwalkmarina.com/dine/the-blind-tiger

3. Shady Gator Lakeview Cafe & Bar

Of all the spots to soak up sunny days, frosty drinks, and sweeping views of Biloxi Beach, the expansive deck at Shady Gator Lakeview Cafe & Bar tops the list. This two-story lakefront oasis transports the easygoing essence of Key West to the heart of Biloxi with casual Caribbean comfort food best enjoyed al fresco.

With live music keeping things festive day and night, visitors watch sailboats skim along Lake Borgne as they sip Gator Bait Bushwackers garnished with an entire slice of sugarcane. Menu favorites include conch fritters, coconut shrimp, lobster mac ‘n’ cheese, blackened catch platters, and the Floribbean Fish Sandwich piling golden fried red snapper atop honey mustard slaw between perfectly griddled buns.

Shady Gator doesn’t pretend to offer fine dining – instead it captures the quintessential Gulf Coast experience of sea breezes, sunshine, and good times shared over flavor-packed fare and frosty drinks by the water.

Address: 1214 Beach Blvd, Biloxi, MS 39530

Hours: Mon-Fri, 11am–10pm; Sat-Sun, 8am–10pm

Contact: (228) 388-1633; shadygatorbiloxi.com

4. White Cap Seafood

Steeped in nostalgia, White Cap Seafood has been transporting diners to Biloxi’s golden days as a vacation hotspot since the 1950’s. Between postcard-worthy views of the peninsula and Back Bay Bridge from its windows and patio seating, visitors enjoy timeworn combo platters starring regional specialities.

Fried favorites feature golden brown jumbo Gulf shrimp, whole stuffed flounder, crawfish tails, stuffed crab and mouthwatering hushpuppies. Oysters arrive fresh shucked or blazing hot in the half-shell straight from the in-house raw bar – said to be one of the best around. Classics like blackened redfish, seafood gumbo overflowing with crab and shrimp, and crisp iceberg wedge salads topped with lump blue crab round out the menu.

For those really wanting to indulge, there’s always the colossal baked stuffed shrimp baked in seasoned butter then dosed in buttery white wine parsley sauce. 70 years strong, White Cap Seafood continues living up to its stellar reputation for heritage-driven cooking and splendid views.

Address: 280 Beach Blvd, Biloxi, MS 39530

Hours: Mon-Sat, 11am–10pm; Sun, 11am–9pm

Contact: (228) 435-1710; whitecapseafood.com

5. Mary Mahoney’s Old French House

With a legacy spanning over four decades, Mary Mahoney’s commands attention as one of Biloxi’s most iconic and enduring restaurants. Set inside a stunning 1860’s home perched on well-manicured grounds dotted with murals, fountains and lush greenery, this historic Gulf Coast institution charms guests with its antebellum architecture before they even step inside.

Once in the elegant yet inviting dining rooms awash in stained glass, antiques, and local art, the real magic begins. Renowned for its impeccable takes on French Creole classics, highlights range from turtle soup and fried green tomatoes to bronzed redfish dripping in spiced butter and vegetable-stuffed jumbo lump crab topped in Champagne cream sauce.

Desserts steal the show with creative takes on Southern sweets like their signature White Chocolate Bread Pudding or sweet potato cheesecake. For lovely ambiance, attentive service and outstanding Creole flavors that stand the test of time, Mary Mahoney’s is undoubtedly a Biloxi treasure.

Address: 1351 East Howard Avenue Biloxi, MS 39530

Hours: Mon-Sat, 5–10pm; Sun brunch, 10:30am–2pm

Contact: (228) 374-5646; marymahoneysbiloxi.com

6. The Roosevelt Hotel Restaurant & Bar

Calling the vibrant, art-filled dining room at the Roosevelt Hotel home, the creatively named hotel restaurant invites guests to soak in splendid harbor views along with elevated Southern fare focused on Gulf ingredients.

As the only Forbes Four-Star diamond restaurant along the entire Mississippi Gulf Coast, this refined venue sets the bar high starting with extensive wine pairings and table-side preparations. Appetizers range from Southern staples like fried green tomatoes with goat cheese to contemporary starters like prosciutto-wrapped pears with gorgonzola drizzle.

Select from seafood chowders, delicate salads and regional delights before progressing to entrees starring plump Gulf shrimp, buttery filets or bronzed flounder with crabmeat stuffing in tangy Creole sauce. For more casual cocktails and eats in a historical setting, the breezy Harbor View Bar & Grill beckons just off the lobby. With its storied past playing host to the likes of Elvis Presley and Frank Sinatra, the Roosevelt presents a special night on the town.

Address: 140 Harrison Avenue Biloxi, MS 39530

Hours: Tue-Sat 6–10pm

Contact: (228) 386-1000; therooseveltrestaurants.com

7. Pepe’s on the River

Colorful Pepe’s on the River is a perennial local favorite for sizable frosted margaritas, live bands, and contemporary Mexican fare paired with Southern hospitality. Overlooking the Tchoutacabouffa River, the sprawling indoor and covered al fresco spaces host everything from casual family meals to special celebrations under strings of twinkly lights.

Their scratch-made guacamole, table-side flaming cheese dip, and sizzling fajita platters pair perfectly with Gulf catches like crunchy shrimp tacos, citrusy ceviche tostadas and generously stuffed redfish envueltos. Local beers, frosty hurricanes and sugarcane skinny margaritas top tables while patrons sway to frequent live music performances ranging from jazz trios to salsa dancing.

With a lively bar scene after dark and impressive weekend brunch buffet spread, Pepe’s remains a quintessential Biloxi destination for festive riverfront dining morning to night.

Address: 1118 Beach Blvd, Biloxi, MS 39530

Hours: Sun-Thu, 11am–10pm; Fri-Sat, 11am–11pm

Contact: (228) 388-2292; pepesbiloxi.com

8. Brick & Spoon

Tucked away in a tree-lined Biloxi neighborhood, cozy brunch nook Brick & Spoon couples down-home charm with big, brilliant flavors inspired by the owners’ global travels to Morocco, Asia and Latin America. Weekend mornings see queues trailing out the door as folks vie for blackened shrimp burritos drenched in spicy habanero sauce, crispy crab cake Benedict topped with garlic shallot butter and fluffy sweet potato pancakes.

Locally roasted coffees pair nicely with signature beignets showered in powdered sugar or sticky buns overflowing with pecans then crowned with cream cheese frosting. Later on, Brick & Spoon transitions into a laidback lunch, happy hour and dinner destination dishing out international small plates alongside regional bites.

Think falafel fritters with mint raita, pork belly banh mi sandwiches, chicken tikka masala flatbreads and “Krispy Krunch” buttermilk fried chicken with spicy honey drizzle and jalapeño slaw over fries or waffles. Whatever time of day, Brick & Spoon’s creative comfort foods never disappoint.

Address: 969 Cedar Lake Rd Suite A, Biloxi, MS 39532

Hours: Sat-Sun, 8am-2pm; Mon, Wed-Fri 11:30am-8:30pm

Contact: (228) 354-2016; brickandspoonbiloxi.com

9. Cafe Climb

Soaring over the Back Bay on stilts surrounded by sprawling Live Oaks, this tucked away cottage style cafe pairs postcard views with equally vivid flavors. Chef proprietor Regan West elevates approachable Southern fare by weaving global accents into local staples for a taste of Biloxi through a well-stamped passport.

Visitors sip Manhattans and nibble pimento cheese fritters beside floor-to-ceiling windows revealing stunning vistas across Biloxi Bay as fishing trawlers putter through the marsh grasses below.

Mains span seared diver scallops on creamy cheese grits to chicken & andouille sausage gumbo bursting with regional spices. For the full experience, the Chef’s Blind Tasting Menu lets West’s seasonal inspirations shine through as many as ten courses paired with boutique wines – all enshrouded in mystery until served.

Perched high over serene wetlands with superb dining and dreamy views at every turn, Cafe Climb lets visitors fall for Biloxi’s beauty one delicious bite at a time.

Address: 1092 Beach Blvd Suite A, Biloxi, MS 39530

Hours: Tue-Sat 5–9pm

Contact: (228) 432-0515; cafeclimb.com

10. Fill-Up with Billups

From the cheeky name referencing a hearty meal to the scratch-made Southern staples filling plates and bellies, Fill Up with Billups keeps things light while seriously satisfying. Tucked away just off Highway 90, this counter-service storefront dishes out crispy fried favorites from catfish to pork chops alongside burgers and po boys stacked sky-high.

Daily specials highlight regional fare with barbecued smoked sausage links, butter beans and cabbage or chicken and dumplings joining daily rotations – all under $10. Enjoy picnic table seating out front or order classic sweets like banana pudding and peach cobbler to go.

No matter what guests choose off the always affordable menu at Billups, piping hot comfort foods served up with genuine hospitality makes this roadside jewel is a true local treasure.

Address: 4229 Bienville Blvd Suite B, Biloxi, MS 39531

Hours: Tue-Sat, 11am-7pm

Contact: (228) 392-5814; fillupwithbillups.com

11. COAST Seafood & Brew

With pristine views over sugary white sands to the Gulf of Mexico’s shimmering blues beyond, COAST celebrates hyper-local flavors starting with the daily catch cooked over a live oak wood fire. Perched right on the sand, the laid back surf shack ambiance lets the scenery steal the spotlight through wall-sized retractable windows revealing sweeping vistas.

Giant peel-and-eat shrimp arrive steaming hot alongside Southern sides like hushpuppies, fried pickles and hand cut fries with malt vinegar aioli. Move onto the rotating “fresh catch” expertly blackened, bronzed or grilled, or opt for po’ boys and tacos piling the day’s haul onto crunchy breads and wraps. Dozens of national and local beers available by bottle or draft provide liquid courage for a dip in the Gulf right out front!

With ultra fresh seafood, stunning views of Biloxi Beach out every window and toe-sinking sand between the toes, COAST delivers destination dining with local flair.

Address: 790 Beach Blvd, Biloxi, MS 39530

Hours: Daily, 11am-10pm

Contact: (228) 229-7928; coastseafoodandbrew.com

12. Doris Metropolitan

The glittering high rise towers of Biloxi’s Beau Rivage Resort & Casino play home to the Mississippi Gulf Coast’s sole destination for internationally inspired interpretations of fine dining favorites. Doris Metropolitan transports guests across continents with an innovative “East meets West” menu fusing beloved staples from the Levant region with all-American preparations and prime cuts.

Their expansive patio overlooking serene views of the Mississippi Sound provides a stunning backdrop for sharing Mediterranean and Middle Eastern small plates like labneh, falafel, babaganoush and kebabs.

From the exhibition kitchen, dynamic table-side presentations dazzle patrons while expert chefs slice, torch, and prepare premium steaks, seafood and chops cooked over fragrant hardwood charcoals.

With fine wines, craft cocktails like their Negroni flight and warm hospitality under the stars, Doris Met transports with world class ambiance and globally inspired flavors befitting Biloxi’s sparkling shores.

Address: Beau Rivage Resort & Casino, 875 Beach Blvd Biloxi, MS 39530

Hours: Sun-Thu, 5-10pm; Fri-Sat, 5-11pm; Sat-Sun, Brunch, 10am-3pm

Contact: (228) 386-7271; dorismetropolitan.com

Conclusion

From heritage icons serving up quintessential Gulf fare to contemporary innovators fusing global accents into regional specialties, Biloxi offers an extraordinary range of dining opportunities to delight every palate.

Visitors can embark on an around-the-world culinary adventure without ever leaving sight of the shimmering Mississippi Sound thanks to the tasty variety its restaurants provide.

Beyond outstandingly fresh seafood reflective of a historic fishing town, creative takes on American and international comfort foods present exciting new flavors to discover.

Whether planning a celebratory indulgence or casual meal, foodies find their fix among white linens and wine pairings or out under the stars slurping oysters with plastic forks.

From upscale to down-home, harborfront to neighborhood, Biloxi’s eclectic food scene invites diners to grab a seat and dig in to well-earned reputation as Mississippi’s culinary crown jewel.

Leave a Comment